Generated by All in One SEO v5.0.1.1, this is an llms.txt file, used by LLMs to index the site. # CircaMS Exploring Circadian Rhythmicity in Multiple Sclerosis ## Sitemaps - [XML Sitemap](https://circams.ca/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Blog](https://circams.ca/blog/) - The CircaMS Blog is a space for sharing and learning about MS and circadian rhythms. Want to stay in the loop with our study? We will be posting updates on this page, as well as pieces about other research in the field. Take the Survey - [Pain is complex: Let’s talk about it](https://circams.ca/2025/09/24/pain-is-complex-lets-talk-about-it/) - The relationship between pain and Multiple Sclerosis Everyone has experienced pain at least once in their life, whether trying to remove a hot meal from the oven or stubbing their toe on the couch. Pain is a part of everyday life for many people living with MS, and it is usually more than just a - [MS Hear From The Experts](https://circams.ca/2025/08/08/ms-hear-from-the-experts/) - Register here for the MS Hear From The Experts presented by MS Canada: https://mscanada.ca/ms-hear-from-the-experts-webinars This informative webinar is designed to empower people affected by multiple sclerosis. Don’t miss this free event on August 13th from 6-7pm ET! - [What is multiple sclerosis? Understanding how MS affects the nervous system](https://circams.ca/2025/06/24/what-is-multiple-sclerosis-understanding-how-ms-affects-the-nervous-system/) - Multiple sclerosis (MS) is a lifelong condition that affects the central nervous system, including the brain and spinal cord (Ghasemi et al., 2017). In people with MS, the body’s immune system accidentally attacks myelin; the protective “coating” covering the axons: which are “wires” that extend from a nerve cell (neuron). This system works together to - [World MS Day](https://circams.ca/2025/05/30/world-ms-day/) - Every five minutes, someone, somewhere in the world, is diagnosed with MS. The #MyMSDiagnosis campaign advocates for early and accurate diagnosis for everyone living with MS. It highlights the global barriers to diagnosing MS, raising awareness by sharing real stories and data. Learn more about the signs and challenges of diagnosis through the free online - [The CircaMS study is now available in Canada and United States!](https://circams.ca/2025/03/20/the-circams-project-is-now-available-in-canada-and-united-states/) - Welcome to the CircaMS study! CircaMS was built by an interdisciplinary group of researchers and clinicians based in Kingston, Ontario. Our study aims to better understand how the symptoms experienced by people with MS can fluctuate daily, and why these fluctuations might be important for MS management. We are particularly interested in exploring the relationship - [May is MS awareness month!](https://circams.ca/2025/05/14/may-is-ms-awareness-month/) - May is Multiple Sclerosis Awareness month! Canadians have one of the highest rates of MS in the world and, on average, 12 Canadians are diagnosed with this unpredictable disease every day. We don’t have a cure, yet! But we are hopeful for the future of MS research.This month is dedicated to MS, and there are - [Understanding Ecological Momentary Assessments (EMA)](https://circams.ca/2023/10/23/understanding-ecological-momentary-assessments-ema/) - In the intricate world of epidemiological research, a powerful tool known as Ecological Momentary Assessment (EMA) allows us to explore the nuances of human behavior, thoughts, and emotions catching them within their natural habitat. What is EMA? Ecological Momentary Assessment, or EMA, is a method that reaches outside the boundaries of traditional assessment, allowing us - [Understanding Baseline Questionnaires: What to Expect and Why They Matter](https://circams.ca/2024/01/26/understanding-baseline-questionnaires-what-to-expect-and-why-they-matter/) - As you know, MS is a chronic and highly variable disease that often leads to difficulty with daily activities and challenges to quality of life. However, not everyone experiences symptoms of MS in the same way, and some people have patterns of symptoms (like fatigue and pain) that others do not. In our CircaMS - [Decoding the Scientific Link Between MS and Depression](https://circams.ca/2023/11/12/decoding-the-scientific-link-between-ms-and-depression/) - Multiple Sclerosis is a complex neurological disorder that affects both physical symptoms and mental wellbeing. People with MS often also suffer from mood disorders associated with their disease, and the scientific community has been researching the intricate relationship between these two conditions. Today we will explore the link between MS and mood disorders. The Neurological - [The Future of MS Treatment: Personalized Approaches Based on Circadian Rhythmicity](https://circams.ca/2023/11/21/the-future-of-ms-treatment-personalized-approaches-based-on-circadian-rhythmicity/) - The search for more effective treatments for conditions like Multiple Sclerosis (MS) is an ongoing journey. MS treatments that take into consideration an individual’s biological clock, or circadian rhythmicity, have the potential to become a revolutionary approach to managing this challenging disorder. Future Directions Current research into circadian rhythmicity and MS has revealed that dietary - [Shift Work Disruptions and MS Susceptibility](https://circams.ca/2023/11/29/shift-work-disruptions-and-ms-susceptibility/) - The traditional 9-to-5 job is no longer the sole ‘norm’. Shift work, involving irregular hours or night shifts, has become a part of many industries. While it accommodates around-the-clock demands, its impact on health remains a topic of concern. The human body operates on an internal clock known as the circadian rhythm. A mechanism that - [May is MS Awareness month!](https://circams.ca/2024/05/01/ms-is-ms-awareness-month/) - May is Multiple Sclerosis (MS) Awareness Month. Today, I share this digital carnation to #TakeActionForMS and show my support for all Canadians affected by MS. Together with @mscanofficial , we can make a world free of MS a reality. Take the survey here if you live in Kingston, ON Take the survey here if you - [Understanding the role of circadian rhythms in chronic metabolic diseases](https://circams.ca/2024/02/09/understanding-the-role-of-circadian-rhythms-in-chronic-metabolic-diseases/) - The connections between circadian rhythmicity and health outcomes are abundant and are being studied around the world. It is evident that the body's internal circadian clock plays a pivotal role in health, with growing evidence highlighting its significance in both the development and treatment of diseases. Today, we are going to take a closer look - [Understanding the Link Between Circadian Rhythms, Sleep Disorders, and MS](https://circams.ca/2024/11/20/understanding-the-link-between-circadian-rhythms-sleep-disorders-and-ms/) - Living with multiple sclerosis (MS) can feel like an unpredictable journey, with each person’s experience being unique. One of the often-overlooked aspects of MS is its impact on sleep patterns, especially when it comes to circadian rhythms. Let’s explore the connection between circadian rhythm, sleep issues, and how they influence fatigue in people with MS. - [Our Body's Daily Rhythm: How Circadian Clocks Work](https://circams.ca/2023/12/12/our-bodys-daily-rhythm-how-circadian-clocks-work/) - Have you ever noticed how your energy levels ebb and flow throughout the day, seemingly on cue? That's your circadian rhythm: the internal clock that guides your body through its daily routine, right down to the activity of your cells. But how does this rhythm work, and what pathways are involved? Let’s meet some of - [Safeguarding Confidentiality in Research with REDCap](https://circams.ca/2023/10/31/safeguarding-confidentiality-in-research-with-redcap/) - In the ever-evolving landscape of research, ensuring the confidentiality of participants is crucial. With the creation of data management platforms like REDCap (Research Electronic Data Capture), maintaining the integrity of sensitive information has become more manageable than ever before. In this blog post, we will dive into the significance of confidentiality in research and how - [Welcome to the CircaMS survey!](https://circams.ca/2023/10/16/welcome-to-the-website-of-the-circams-project-circams-was-built-by-an-interdisciplinary-group-of-researchers-and-clinicians-based-in-kingston-ontario-our-study-aims-to-better-understand-how-the-sym/) - Welcome to the CircaMS project! CircaMS was built by an interdisciplinary group of researchers and clinicians based in Kingston, Ontario. Our study aims to better understand how the symptoms experienced by people with MS can fluctuate daily, and why these fluctuations might be important for MS management. We are particularly interested in exploring the relationship - [The correlation between latitude and MS incidence](https://circams.ca/2023/06/25/the-correlation-between-latitude-and-ms-incidence/) - What is Multiple Sclerosis? Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. MS targets myelin, which is the insulating layer of the nerves that allows electric signals to transmit more efficiently. While symptoms differ from person to person, multiple sclerosis usually manifests as weakness in the limbs, vision problems, - [What is CircaMS?](https://circams.ca/2023/06/25/getting-to-know-circams/) - Welcome to the website of the CircaMS project! CircaMS was built by an interdisciplinary group of researchers and clinicians based in Kingston, Ontario. Our study aims to better understand how the symptoms experienced by people with MS can fluctuate daily, and why these fluctuations might be important for MS management. We are particularly interested in ## Pages - [Welcome to CircaMS](https://circams.ca/) - Welcome to the website of the CircaMS project! CircaMS was built by an interdisciplinary group of researchers and clinicians based in Kingston, Ontario. Our study aims to better understand how the symptoms experienced by people with MS can fluctuate daily, and why these fluctuations might be important for MS management. We are particularly interested in - [Contact Us](https://circams.ca/contact-us/) - Reach out to the CircaMS Team! Pain Chronobiology & Neuroimmunology LabQueen’s University, Botterell Hall18 Stuart Street, room 773/754Kingston, Ontario, Canada K7L 3N6 Email: circams@ghasemloulab.ca - [Our Team](https://circams.ca/our-team/) - Dr. Nader Ghasemlou Dr. Ghasemlou is an Associate Professor in the Departments of Anesthesiology and Biomedical & Molecular Sciences at Queen’s University, where he leads the Pain Chronobiology & Neuroimmunology Lab. His research team is working at the intersection of neuroimmunology, pain physiology, and circadian biology. Using molecular, cellular, and systems biology, they are working - [FAQ](https://circams.ca/faq/) - What is the purpose of the CircaMS study? Multiple sclerosis is a complex neuroimmune disease that impacts people across the globe. Here in Canada, we have one of the world's highest rates of MS, but despite its prevalence, there is still a lot that we don't know about this condition. We are interested in how - [Privacy Policy](https://circams.ca/privacy-policy/) - Who we are Our website address is: https://circams.ca. We are a group of Canadian researchers, clinicians, and people with lived experience who are interested in understanding the relationship between circadian rhythms and individuals' experiences with Multiple Sclerosis (MS). Comments When visitors leave comments on the site we collect the data shown in the comments form, - [Useful links](https://circams.ca/useful-links/) - Click on the logos below to access helpful MS resources! ## Categories - [Uncategorized](https://circams.ca/category/uncategorized/) - [circadian rhythms](https://circams.ca/category/circadian-rhythms/) - [MS research](https://circams.ca/category/ms-research/) - [CircaMS](https://circams.ca/category/circams/) ## Tags - [ecological momentary assessment](https://circams.ca/tag/ecological-momentary-assessment/) - [MS](https://circams.ca/tag/ms/) - [Circadian Rhythm](https://circams.ca/tag/circadian-rhythm/) - [research](https://circams.ca/tag/research/)